Oil palm is the most important commodity crop for Malaysia and Indonesia. However, it is being threatened by a disease identified as basal stem rot (BSR) caused by Ganoderma spp. Common approaches such as chemical and cultural control have failed to demonstrate total effectiveness in controlling BSR disease. Nevertheless, these practices cause detrimental effects on the environment. Therefore, the attention on adopting biological control agents (BCA) as one of the sustainable methods to eradicate and control BSR disease is on the rise. The current review highlights on the attempts and outcome of applying various BCA such as fungi, bacteria and actinomycetes as single or mixed application to control BSR disease in oil palm.