During the last few years, interest in polyols derived from natural oils has been constantly increasing for a variety of polyurethane applications. Bio-based polyol chemistry brings new product supply options that are produced from renewable resources, have supply stability and provide the opportunity for differentiation in the foam market-place. These are some of the key drivers for the polyurethane processors to look at ways to utilize such products. Until now, the successful use of natural oil-based polyols in flexible slabstock applications has been limited due to issues with quality consistency, odour, impact on physical properties and processing limitations. Most recently, Cargill Incorporated introduced its BiOH^TM polyol product line for the production of flexible foams leveraging on the company’s integrated supply chain and deep knowledge in processing oilseeds and vegetable oils on a global basis. Commercially available BiOH polyols are produced predominantly from soya-based feedstock. However, this article will show that Cargill can produce equally high quality polyols using palm feedstock. BiOH polyols are performance products produced with a chemistry that is completely detached from propylene or ethylene oxide. BiOH polyols have also resolved the odour and quality consistency issues previously encountered with other natural oil-based polyols. This article will describe the large-scale evaluation results of the first generation BiOH polyols in different foam grades and their ability to deliver the following: ease of processing with commercially available catalysts, surfactants and additives; improved flammability; improved hydrolysis resistance; performance enhancement in different foam grades such as viscoelastic; same level of microbial activity; more efficient load-bearing building capabilities than SAN copolymer polyols and smaller environmental footprint.